Chronic lymphoproliferative disorder of natural killer cells
Name: |
Chronic lymphoproliferative disorder of natural killer cells
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Description: |
A rare large granular lymphocyte leukemia characterized by persistent (> 6 months) natural killer cell lymphocytosis in the absence of clinical diagnosis of leukemia/lymphoma, autoimmune disease, or chronic viral infections. The clinical course is variable, but generally indolent. Patients often remain asymptomatic, or may present with clinical manifestations including vasculitic skin lesions, neutropenic infections, musculoskeletal symptoms, peripheral neuropathy, or splenomegaly.
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ORPHAcode: |
512017
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Synonyms: |
CLPD-NK
CNKL
Chronic NK lymphocytosis
Chronic NK-cell lymphocytosis
Chronic lymphoproliferative disorder of NK-cells
NK-cell lineage granular lymphocyte proliferative disorder
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XREF(s): | |
Analyte(s): | |
Created: |
13 May 2019 - 01:02
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Changed: |
22 Jun 2023 - 16:14
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