Genetic tests

Full name Analytes Gene panels Disease Laboratory
Susceptibility to pancreatitis induced by thiopurine immunosuppressants -Pharmacogenetics Azathioprine or 6-mercatopurine toxicity or dose selection Centre de Génétique Humaine - CHU Sart-Tilman
Myeloid/lymphoid neoplasms with germline predisposition (gene panel) Hematologic Familiar Forms - ULG Centre de Génétique Humaine - CHU Sart-Tilman
Erythrocytoses, polycythémies, thrombocytoses et neutropénies congénitales (gene panel) Erythocyoses, polycythémies, thrombocytoses congénitales (gene panel) - ULG Centre de Génétique Humaine - CHU Sart-Tilman
Inherited Kidney Diseases (Gene Panel) Panel Nephro-ULG-V1 Centre de Génétique Humaine - CHU Sart-Tilman
Abacavir toxicity (HLA-B*57:01 genotyping) - Pharmacogenetics HLA-B Abacavir toxicity Centre de Génétique Humaine - CHU Sart-Tilman
CYP3A5*3 genotyping - drug metabolism - Pharmacogenetics CYP3A5 Tacrolimus dose selection Centre de Génétique Humaine - CHU Sart-Tilman
Leri-Weill dyschondrosteosis / ISS SHOX Léri-Weill dyschondrosteosis, SHOX-related short stature Centre de Génétique Humaine - CHU Sart-Tilman
Obesitas, Monogenic early onset MC4R Obesity due to melanocortin 4 receptor deficiency Centre de Génétique Humaine - CHU Sart-Tilman
Somatic analysis of the BRCA genes in the context of ovarian cancer treatment (BRCA1; BRCA2 genes) BRCA1, BRCA2 Centre de Génétique Humaine - CHU Sart-Tilman
Gilbert disease / Irinotecan sensitivity / Raltegravir toxicity - Pharmacogenetics UGT1A1 Gilbert syndrome (NON RARE IN EUROPE), Irinotecan toxicity Centre de Génétique Humaine - CHU Sart-Tilman
Thiopurine S-Methyltransferase deficiency - TPMT genotyping - TPMT*2/ TPMT*3A/3B/3C - Pharmacogenetics TPMT Azathioprine or 6-mercatopurine toxicity or dose selection Centre de Génétique Humaine - CHU Sart-Tilman
Beta-globin hemoglobinopathies (Hot-spot mutations : Sickle cell disease (HBS), hemoglobin C, hemoglobin E or Hemoglobin D) HBB Sickle cell anemia, Hemoglobin C disease, Hemoglobin E disease, Hemoglobin D disease, Delta-beta-thalassemia, Sickle cell-beta-thalassemia disease syndrome, Beta-thalassemia intermedia, Beta-thalassemia major Centre de Génétique Humaine - CHU Sart-Tilman
Microsatellites instability analysis- MMR genes MLH1, MSH2, MSH6, PMS2 Lynch syndrome, Constitutional mismatch repair deficiency syndrome Centre de Génétique Humaine - CHU Sart-Tilman
Lynch syndrome - MLH1 promoter hypermethylation and BRAF V600E mutation MLH1, BRAF Selection of therapeutic option in colorectal cancer Centre de Génétique Humaine - CHU Sart-Tilman